All-Star second baseman Robinson Cano of the Seattle Mariners was suspended 80 games without pay by Major League Baseball after he tested positive for a banned substance, it was announced Tuesday. Cano tested positive for the diuretic furosemide, which violates MLB’s drug prevention and treatment program. He said he would accept the suspension, which begins immediately.

Under MLB’s drug policy, a player is not automatically suspended for use of a diuretic unless MLB can prove he intended to use it as a masking agent. A source familiar with the case told ESPN’s T.J. Quinn that Cano tested positive before the season and appealed. During the appeal, MLB apparently was able to determine his intent, which resulted in Cano dropping his appeal, the source said. Cano said he was given furosemide by a licensed doctor in his native Dominican Republic and the substance is used to treat “various medical conditions” there and in the United States.

Cano suffered a fractured fifth metacarpal in his right hand when he was struck by a pitch from Detroit’s Blaine Hardy on Sunday. He was placed on the disabled list Monday and, according to multiple reports, had surgery Tuesday. MLB said Cano’s time on the disabled list will count toward his 80-game suspension. Baseball’s drug program doesn’t distinguish between a healthy and unhealthy player. However, he will lose salary — $11.85 million of his $24 million deal for 2018, according to ESPN’s Darren Rovell — and is ineligible for the postseason and the All-Star Game.

The 35-year-old second baseman spent the first nine years of his career with the New York Yankees, and news of his suspension shocked his former teammates. Cano is one of the Mariners’ biggest stars. He hit 23 home runs last season and 39 in 2016. The eight-time All-Star selection was batting .287 with four home runs and 23 RBIs this season, his fifth with Seattle. Before breaking his hand, Cano hadn’t missed a game this season, and he hasn’t played in fewer than 150 games in any of the past 11 seasons. According to ESPN Stats & Information, Cano’s 1,783 games played since the start of the 2007 season are the most in MLB in that span.

Current Mariners outfielder Dee Gordon was suspended 80 games for violating MLB’s performance-enhancing drug policy while he was with the Marlins in 2016. Mariners general manager Jerry Dipoto said Gordon, a former second baseman, will likely see some time at that position to fill in for the suspended Cano. Current designated hitter Nelson Cruz served a 50-game suspension while with the Rangers in 2013 for violations of the drug agreement, in relation to the sport’s investigation of the Biogenesis of America clinic.

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